RxLink – Glucosamine & Chondroitin Plus with C

RxLink Glucosamine & Chondroitin Plus
With Vitamin C and Bromelain
DESCRIPTION
RxLink Glucosamine & Chondroitin Plus is formulated to help support
healthy joint function by providing nutritional components
necessary for cartilage synthesis and maintenance.
FUNCTIONS
Joint disease, mainly osteoarthritis is a potentially debilitating
condition that affects the soft tissue matrix that “cushions”
our joints. To help support the structural integrity of joint
cartilage, glucosamine and chondroitin offer significant
benefits. Glucosamine and chondroitin sulfate are both
integral components of healthy joint tissue and are the forms
that have been used in the major clinical trials. Glucosamine
sulfate helps support the production, and limit the breakdown
of proteoglycans, a class of compounds that make up the
cartilage matrix of joint tissue.
Chondroitin sulfate has been shown to support the structural
matrix of joints as well as the production of hyaluronic
acid (major component of synovial fluid which keeps joints
“lubricated” and moving freely).
Chondroitin sulfate may also help limit chondrocytes from
producing enzymes and other compounds that stimulate the
breakdown of the cartilage matrix of joint tissue. To help
support healthy cartilage, manganese and vitamin C are added
because they are essential for the production of the collagen
matrix that helps support the structural integrity of cartilage.
INDICATIONS
RxLink Glucosamine & Chondroitin Plus may be a useful dietary
supplement for those who wish to support healthy functioning
and flexibility of the joints by maintaining cartilage integrity.
SUGGESTED USE
Adults take 3 tablets daily at mealtime or as directed by a
healthcare professional.
SIDE EFFECTS
People with shellfish allergies or who are currently taking
anticoagulant medication should consult with their healthcare
professional before taking Glucosamine & Chondroitin Plus.
STORAGE
Store in a cool, dry place, away from direct light. Keep out of
reach of children.
These statements have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat, cure, or
prevent any disease.
FORMULA (RxLink Glucosamine & Chondroitin Plus)
3 Tablets Contain:
Vitamin C (as ascorbic acid) ……………………… ….400 mg
Manganese (as amino acid chelate) …………………. 10 mg
Glucosamine Sulfate …………………………………. 1,500 mg
(from 2,000 mg glucosamine sulfate potassium chloride)
Chondroitin Sulfate Complex …………………….. 1,200 mg
(Standardized to 90% [1,080 mg] Chondroitin Sulfate)
Bromelain (Ananas comosus fruit extract) ……………. 50 mg
(Standardized to 1,800 GDU*/gm)
*GDU (Gelatin Digestive Units) are a measure of the relative strength of
digestive aids.
Other Ingredients: dicalcium phosphate, cellulose, modified
cellulose gum, magnesium stearate, and silica. Contains
shellfish and soy.
This product contains NO sugar, salt, dairy, yeast, wheat,
gluten, corn, preservatives, artificial colors or flavors.
REFERENCES
Braham R, Dawson B, Goodman C. The effect of glucosamine
supplementation on people experiencing regular knee pain. Br J Sports Med
2003;37:45-9.
Bruyere O, Pavelka K, Rovati LC, et al. Total joint replacement after
glucosamine sulphate treatment in knee osteoarthritis: results of a mean
8-year observation of patients from two previous 3-year, randomised, placebo
controlled trials. Osteoarthritis Cartilage 2008;16:254-60.
Persiani S, Rotini R, Trisolino G, et al. Synovial and plasma glucosamine
concentrations in osteoarthritic patients following oral crystalline glucosamine
sulphate at therapeutic dose. Osteoarthritis Cartilage 2007;15:764-72.
Hoffer LJ, Kaplan LN, Hamadeh MJ, et al. Sulfate could mediate the
therapeutic effect of glucosamine sulfate. Metabolism 2001;50:767-70.
Gabay C, Medinger-Sadowski C, Gascon D, et al. Symptomatic effect of
chondroitin 4 and chondroitin 6 sulfate on hand osteoarthritis: a randomized,
double-blind, placebo-controlled clinical trial at a single center. Arthritis
Rheum 2011;63:3383-91.
Kelly GS. The role of glucosamine sulfate and chondroitin sulfates in the
treatment of degenerative joint disease. Altern Med Rev 1998;3:27-39.
Knudsen J, Sokol GH. Potential glucosamine-warfarin interaction resulting
in increased international normalized ratio: Case report and review of the
literature and MedWatch database. Pharmacotherapy 2008;28:540-8.
Danao-Camara T. Potential side effects of treatment with glucosamine and
chondroitin. Arthritis Rheum 2000;43:2853.
Rozenfeld V, Crain JL, Callahan AK. Possible augmentation of warfarin effect
by glucosamine-chondroitin. Am J Health Syst Pharm 2004;61:306-307.
Leeb BF, Schweitzer H, Montag K, Smolen JS. A meta-analysis of chondroitin
sulfate in the treatment of osteoarthritis. J Rheumatol 2000;27:205-11.

Manufactured For:
RxLink Pharmaceuticals
Appleton, WI USA 54912